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SA¹ú¼Ê´«Ä± has partnered with PolitiFact to fact-check Florida politicians. The Pulitzer Prize-winning team seeks to present the true facts, unaffected by agenda or biases.

Days after announcing a push to end Florida’s school vaccine mandates, state Surgeon General Dr. Joseph Ladapo questioned the whooping cough vaccine’s effectiveness.

In a on CNN’s "State of the Union," Ladapo told host Jake Tapper that his how ending the vaccine requirements could affect children’s health or future outbreaks.

"Absolutely not," Ladapo responded, before referring to whooping cough vaccines. "That's an example of a vaccine that is ineffective. The data show that it's ineffective at preventing transmission."

, or whooping cough, is a highly contagious bacterial infection that can cause uncontrollable coughing fits. Its common name comes from the sound of infected infants and children make when they try to catch their breath in between coughs.

Like many vaccines, the DTaP vaccine — which stands for diphtheria, tetanus and acellular pertussis — is not a perfect barrier, but it significantly lowers the risk of severe disease.

The DTaP vaccine is 98% effective in children within a year of their last dose, and about 71% effective five years after the last dose,

"The core misunderstanding here is making perfect the enemy of the good," said Dr. Christoph Diasio, a pediatrician at Sandhills Pediatrics in North Carolina. "We would love a 100% perfect magic shield against pertussis — the vaccine protection does wane, it's not perfect — but that doesn't mean that it is useless. It is much much better to get protection from the vaccine rather than to be totally vulnerable to a disease so terrible you can break ribs."
The used in the U.S. since the 1990s is less effective at preventing transmission than its whole-cell predecessor, . But widespread vaccination — which school vaccine mandates are based on — reduces overall transmission by lowering the number of susceptible people.

"The whole-cell pertussis vaccine, while more effective, also caused more side effects because it had more antigens in it," Dr. Jason Terk, a pediatrician at Cook Children’s Health Care System in Texas, said. "The 5 cents of truth in his statement relates to it being comparatively less effective than what we used to use."

Emily Oster, a health economist and founder of , said Ladapo’s statement about the vaccine’s effectiveness regarding transmission is "broadly" true, but noted that the rationale for school vaccination rules is that viruses have trouble getting a foothold when more people are vaccinated.

"The vaccine is very protective against infection in individuals," Oster wrote by email. "Yes, it is true that if someone DID get infected they might pass it along, but if the virus is constantly running into people with vaccination, it will die."

PolitiFact reached out to Florida’s health department about Ladapo’s comment but did not hear back by publication.

How the vaccine works 

Whooping cough can be extremely serious in babies and young children, causing vomiting, pneumonia, convulsions, apnea, brain damage or death. Infants can turn blue during coughing spells because of lack of oxygen. In teens and adults, the disease can cause weight loss, bladder control loss and passing out. Severe coughing can cause rib fractures.

Doctors typically administer the in five doses to patients from infancy through early childhood to help build up immunity and ensure protection doesn’t fade. against the diseases are available for older children, adolescents and adults.

Before pertussis vaccines became available in the 1940s, was one of the more common childhood diseases in the U.S. Each year, as many as 200,000 children got sick and around 9,000 died,

Once the vaccine came to market, through the 1980s by more than 90% compared with the pre-vaccine era.

A vaccine shift over safety 

In the 1990s, the U.S. switched to an acellular vaccine, which contains fragments of a pathogen, because it had fewer side effects and still provided coverage. (Whole-cell versions contain the entire pathogen.)

After pertussis cases began to in the early 2000s, the cause and found that the acellular vaccine as the previous whole-cell version, with some evidence that the immune response wanes more quickly. (As a result, an additional dose is now recommended around 11 and 12 years old.)
There could be other factors that explain the uptick: The disease is more quickly detected and recognized, patients have greater access to laboratory diagnostics, and surveillance and health department reporting is stronger.

families school vaccination exemptions or declining routine vaccines.

"The easier it is to get non-medical exemptions, the greater the number of unvaccinated children will be, increasing the likelihood of pertussis outbreaks in schools and communities," the former director of the Clinical Microbiology-Immunology Laboratories at the University of North Carolina Hospitals, . "School age students can bring this highly contagious organism home and infect non-boosted parents and unvaccinated siblings, especially infants."

Oster also that found states that offer personal belief exemptions, and more easily granted exemptions, were associated with increased whooping cough cases. In Florida, their children from vaccine mandates on medical or religious grounds.

, Gilligan also pointed to the of new pertussis strains, which can result in vaccinated people becoming infected but remaining asymptomatic and able to transmit the disease.

that looked at different pertussis immunization practices around the world said that selecting which vaccine to use should be weighed against effectiveness, likelihood of adverse events, cost and pertussis surveillance in the community.

"The vaccine lessens transmission, it doesn't eliminate it, just like influenza, RSV, rotavirus vaccines — they lessen transmission," said Dr. Paul Offit, director of the Vaccine Education Center at the Children’s Hospital of Philadelphia. "With SARS-CoV-2, (the virus that causes COVID-19), which is similar, if you lived in a highly vaccinated area, you were much less likely to get the disease even if you weren’t vaccinated."

Ultimately, health officials decided that the safety benefits of the acellular pertussis vaccine outweighed the more effective, more reactive whole-cell version. It still offered protection, they said, particularly in shared spaces like schools, when most children were vaccinated.

"There have been no serious safety signals in the 30 years since the DTaP vaccination has been on the market," Terk, the Texas pediatrician, said.

In Florida, the school requirement for the DTaP vaccine for . The state health department told The Associated Press it submitted a rule change Sept. 3 to remove vaccine requirements for chickenpox, hepatitis B, Haemophilus influenza type b (Hib), and pneumococcal diseases for schoolchildren. That’s expected to go into effect around December 2025.

Other vaccines, such as those for measles, polio and whooping cough will require legislative action to be removed. Florida lawmakers aren’t scheduled to meet again until January 2026.

Our Sources

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• Tampa Bay Times, , Sept. 7, 2025
• The Associated Press, , Sept. 7, 2025 
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• Nemours Kids Health, , Reviewed December 2024
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• American Society for Microbiology, , Oct. 21, 2022
• The U.S. Centers for Disease Control and Prevention, , Volume 27, Number 6 — June 2021 
• JAMA Network, , March 15, 2016 
• FloridaHealth.gov, , Updated Aug. 28, 2025
• Johns Hopkins Bloomberg School of Public Health, International Vaccine Access Center, , Aug. 20, 2025
• ProPublica, , April 11, 2025 
• The New York Times, , Dec. 28, 2024
• Email interview Dr. Christoph Diasio, pediatrician at Sandhills Pediatrics in North Carolina, Sept. 8, 2025
• Email interview, Dr. Jason Terk, pediatrician at Cook Children’s Health Care System in Texas, Sept. 8, 2025
• Phone interview, Dr. Paul Offit, pediatrics professor in the Children’s Hospital of Philadelphia’s infectious diseases division and director of its Vaccine Education Center, Sept. 9, 2025
• Email interview, Emily Oster, economist who researches health and statistical methods and founder of ParentData, Sept. 9, 2025
• Email interview, Dr. Otto Ramos, pediatric epidemiologist for Nicklaus Children's hospital in Miami, Sept. 9, 2025